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Concomitant usage of NEXLIZET or NEXLETOL with increased than twenty mg of simvastatin or forty mg of pravastatin need to be avoided due to probable for improved hazard of simvastatin- or pravastatin-connected myopathy.

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Zhang et al. [eighty one] designed and well prepared three courses of multi-goal inhibitors based around the extensive sequence homology along the kinase area of angiogenic RTKs. Organic evaluation indicated that these multi-concentrate on inhibitors exhibited sizeable probable as novel anti-angiogeneic and anticancer brokers.

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Concomitant use of NEXLIZET or NEXLETOL with greater than 20 mg of simvastatin or 40 mg of pravastatin needs to be averted because of the likely for amplified risk of simvastatin- or pravastatin-relevant myopathy.

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